The 9th edition of Seidel’s Guide to Physical Examination offers a comprehensive and patient-centered approach to physical examination and health assessment throughout all stages of life. This edition prioritizes patient safety, evidence-based practice, and clinical reasoning, while also emphasizing effective communication skills and hands-on examination techniques. The core chapters are organized into four main sections, covering Anatomy and Physiology, Review of Related History, Examination and Findings, and Abnormalities, with a focus on integrating lifespan content into each section. The authors, who are advanced practice nurses and physicians with extensive experience in caring for patients of all ages, provide an interprofessional and interdisciplinary perspective. Additionally, this edition features updated content on infectious outbreaks like Zika and Ebola, addressing the importance of infection control measures.